New Orleans will take on their second AFC West opponent when they host the Los Angeles Chargers (7:15 p.m. CDT) in the Mercedes-Benz Superdome. The Saints 3rdprimetime game of the season will be the first meeting between the two clubs on Monday Night Football. Quarterback Drew Brees was originally selected by the Chargers in the second round (32nd overall) of the 2001 NFL Draft and played for them his first five seasons until signing with New Orleans as an unrestricted free agent in 2006.

History: New Orleans Saints vs. Los Angeles Chargers

The Chargers lead the all-time series against the Saints 7-5, but New Orleans has captured the last three matchups in games played in London (2008), New Orleans (2012) and San Diego (2016). Even though the Saints and Chargers haven't played each other in the regular season since a 35-34 win at San Diego's Qualcomm Stadium on October 2, 2016, the two clubs have played each other the last three preseasons in Southern California, preceded by joint practices.

Players and Coaches to Know

Los Angeles Chargers

Head Coach: Anthony Lynn
Quarterback: Tyrod Taylor/Justin Herbert
Key Position Players: WR Keenan Allen, DE Joey Bosa, TE Hunter Henry, RB Austin Ekeler

New Orleans Saints

Head Coach: Sean Payton
Quarterback: Drew Brees
Key Position Players: RB Alvin Kamara, WR Michael Thomas, DE Cameron Jordan