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Get postgame reactions from New Orleans Saints quarterback Taysom Hill and Saints players

John DeShazier analyzes the Malcolm Jenkins interception against the San Francisco 49ers in Week 10 of the 2020 NFL season on this week's Expert Analysis presented by Microsoft Surface.

Game action photos from the New Orleans Saints vs. San Francisco 49ers matchup in Week 10 of the 2020 NFL season.

Defense intercepted two passes, special teams recovered two muffed punts in 27-13 victory

Get postgame reactions from New Orleans Saints quarterback Drew Brees and Saints players

Get postgame reactions from New Orleans Saints head coach Sean Payton

Alvin Kamara led offense, Marquez Callaway recovered two fumbles on special teams

Saints-49ers Postgame - defensive end Cameron Jordan postgame interview following the Saints' 27-13 win vs the San Francisco 49ers in week 10 of the 2020 NFL season.

Saints-49ers Postgame - quarterback Drew Brees postgame interview following the Saints' 27-13 win vs the San Francisco 49ers in week 10 of the 2020 NFL season. Brees suffered an upper-body injury in the first half of the win.

Saints-49ers Postgame - linebacker Demario Davis postgame interview following the Saints' 27-13 win vs the San Francisco 49ers in week 10 of the 2020 NFL season.

Watch the most dynamic plays made by New Orleans Saints running back Alvin Kamara in his Week 10 matchup versus the San Francisco 49ers.

Saints improve to 7-2 with sixth consecutive victory

Saints-49ers Postgame - quarterback Jameis Winston postgame interview following the Saints' 27-13 win vs the San Francisco 49ers in week 10 of the 2020 NFL season.

Saints-49ers Postgame - wide receiver Marquez Callaway postgame interview following the Saints' 27-13 win vs the San Francisco 49ers in week 10 of the 2020 NFL season.

Saints-49ers Postgame - defensive back C.J. Gardner-Johnson postgame interview following the Saints' 27-13 win vs the San Francisco 49ers in week 10 of the 2020 NFL season.

Saints-49ers Postgame - saftey Malcolm Jenkins postgame interview following the Saints' 27-13 win vs the San Francisco 49ers in week 10 of the 2020 NFL season.

Saints-49ers Postgame - running back Alvin Kamara postgame interview following the Saints' 27-13 win vs the San Francisco 49ers in week 10 of the 2020 NFL season.

Saints-49ers Postgame - Head Coach Sean Payton postgame interview following the Saints' 27-13 win vs the San Francisco 49ers in week 10 of the 2020 NFL season.

Jameis Winston, Taysom Hill replace Drew Brees due to injury in second half

Highlights from the New Orleans Saints week 10 win vs the San Francisco 49ers during the 2020 NFL season.

New Orleans Saints cornerback Patrick Robinson high-points the ball in the end zone for a big interception vs the San Francisco 49ers during the 2020 NFL season.

New Orleans Saints running back Alvin Kamara with his third touchdown of the game in week 10 vs the San Francisco 49ers during the 2020 NFL season.

New Orleans Saints wide receiver Marquez Callaway collects his second muffed punt of the game vs the San Francisco 49ers during the 2020 NFL season.

Game action photos from the New Orleans Saints vs. San Francisco 49ers matchup in Week 10 of the 2020 NFL season.

'New Orleans Saints safety Malcolm Jenkins reads Nick Mullens' eyes and gets the finger tip pick vs the San Francisco 49ers in week 10 of te 2020 NFL season.

New Orleans Saints quarterback Jameis Winston throws an 11-yard pass to wide receiver Deonte Harris vs. the San Francisco 49ers during the 2020 NFL season.

New Orleans Saints fans and cheer on the team from inside the Mercedes-Benz Superdome against the San Francisco 49ers in Week 10 of the 2020 NFL season.

Drew Brees took hard hit in second quarter

New Orleans Saints quarterback Drew Brees throws a 3-yard touchdown pass to running back Alvin Kamara vs the San Francisco 49ers during the 2020 NFL season.

Saints are on a five-game winning streak

Saints fans compete in a football-style combine on the Superdome turf on Halftime Hustle for the Saints-49ers week 10 game during the 2020 NFL season.

New Orleans Saints running back Alvin Kamara takes a screen pass 34 yards vs the San Francisco 49ers in week 10 of the 2020 NFL season.

New Orleans Saints defensive end David Onyemata tackles San Francisco 49ers running back Jerrick McKinnon to force a turnover on downs in week 10 of the 2020 NFL season.

New Orleans Saints fans cheer on the team from a safe distance as the Saints take on the San Francisco 49ers in Week 10 of the 2020 NFL season.

New Orleans Saints running back Alvin Kamara with the touchdown run off the toss play vs the San Francisco 49ers during the 2020 NFL season.

New Orleans Saints wide receiver Marquez Callaway with the heads-up fumble recovery on the punt vs the San Francisco 49ers during the 2020 NFL season.

New Orleans Saints kick returner Deonte Harris returns a kickoff 75 yards vs the San Francisco 49ers in week 10 of the 2020 NFL season.

New Orleans Saints linebacker Demario Davis sacks San Francisco 49ers quarterback Nick Mullens in week 10 of the 2020 NFL season.

Demario Davis and Drew Brees get the Saints going with the Saints Pregame Huddle ahead of their week 10 matchup against the San Francisco 49ers during the 2020 NFL season.

Shamarr Allen performs the National Anthem ahead of the New Orleans Saints Week 10 matchup against the San Francisco 49ers presented by Community Coffee.

Actors Jennifer Finnigan and Jonathan Silverman get HYPED for the New Orleans Saints vs. San Francisco 49ers game in week 10 of the 2020 NFL season.

Saints fans ROLL CALL presented by Zatarain's prior to week 10 against the San Francisco 49ers during the 2020 NFL season.

Chat live with Todd Graffagnini throughout the game

Pregame photos from the New Orleans Saints playing host to the San Francisco 49ers in Week 10 of the 2020 NFL season.

Dwayne Washington is inactive

Your Saintsations get Saints fans ready for the team's return to the Mercedes-Benz Superdome!

Sean Payton: 'There's just such a passion with our fan base that that little bit matters'

Get ready for our Week 10 matchup against the San Francisco 49ers on Nov. 15 at 3:25 p.m. on FOX.

Having 'good eyes' will be critical for New Orleans Saints defense against San Francisco

New Orleans Saints players discuss their Week 10 matchup vs. the San Francisco 49ers in our BOSE Soundbites of the Week.