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The New Orleans Saints host the Indianapolis Colts at the Mercedes-Benz Superdome on Monday, December 16, 2019.

Get postgame reactions from Indianapolis Colts head coach Frank Reich and quarterback Jacoby Brissett

Get postgame reactions from Josh Hill, Michael Thomas, and Cameron Jordan

Read what Brees had to say about his record-setting game

Read what Coach Payton had to say in his postgame press conference

Record-setting game for Drew Brees, Saints

The Superdome goes wild for New Orleans Saints quarterback Drew Brees' record 540th touchdown.

The New Orleans Saints celebrate the Week 15 win over the Indianapolis Colts inside the locker room presented by Mercedes-Benz.

Saints quarterback Drew Brees recaps his record breaking performance in tonight's 31-7 victory over the Indianapolis Colts

Saints head coach Sean Payton recaps tonight's 34-7 victory over the Indianapolis Colts

Take a look at New Orleans Saints safety C.J. Gardner-Johnson's best plays from Week 15 on Monday Night Football against the Indianapolis Colts.

New Orleans Saints quarterback Drew Brees continued to rewrite the record books against the Indianapolis Colts. Here are his Week 15 from Monday Night Football.

New Orleans Saints wide receiver Michael Thomas continued his record-breaking season against the Indianapolis Colts. Take a look at his Week 15 highlights from Monday Night Football.

Watch the Indianapolis Colts vs. New Orleans Saints highlights Week 15 of the 2019 season.

Members of the 2009 Super Bowl team honored at halftime during the Saints vs. Colts game at the Mercedes-Benz Superdome.

Drew Brees sets NFL record for touchdown passes, completion percentage in front of a national audience

New Orleans Saints fans cheer on the team against the Indianapolis Colts at the Mercedes-Benz Superdome.

New Orleans Saints quarterback Drew Brees celebrates setting the NFL record for touchdown passes with 540, surpassing Peyton Manning.

He was 29 of 30 for 307 yards with four touchdowns

New Orleans Saints quarterback Drew Brees adds to his touchdown record with 28-yard strike to Taysom Hill.

Brees broke Peyton Manning's record for TD passes in masterful 'Monday Night Football' performance

New Orleans Saints quarterback Drew Brees sets record for NFL all-time passing touchdowns with No. 540.

New Orleans Saints wide receiver Michael Thomas becomes the wide receiver with most 10+ catch games in single season (eight).

The New Orleans Saints host the Indianapolis Colts at the Mercedes-Benz Superdome on Monday, December 16, 2019.

The Saintsations took to the field and performed for fans during Week 15 between the Saints and Colts at the Mercedes-Benz Superdome.

New Orleans Saints players prepare for Week 15 before taking on the Indianapolis Colts at the Mercedes-Benz Superdome.

The New Orleans Saints honored the 2009 team for their Super Bowl victory at halftime of Monday's game against the Indianapolis Colts at the Mercedes-Benz Superdome.

Saints dominate time of possession in first half

New Orleans Saints quarterback Drew Brees lobs 20-yard, flat-footed DIME to Jared Cook.

New Orleans Saints quarterback Drew Brees ties Peyton Manning's all-time pass TD record on 21-yard strike to Smith.

New Orleans Saints wide receiver Michael Thomas one-handed catch is too smooth.

Four TDs vs. Colts moves him past Peyton Manning with 541

New Orleans Saints quarterback Drew Brees slings 15-yard TD pass to wide receiver Michael Thomas with ease.

Four Colts needed to corral New Orleans Saints tight end Jared Cook on 18-yard grab.

New Orleans Saints wide receiver Michael Thomas creates separation for 23-yard catch and run.

Thomas breaks his own record with touchdown reception

New Orleans Saints running back Dwayne Washington bull rushes off edge to block punt.

The New Orleans Saints 2009 Super Bowl team leads the pregame chant prior to kickoff against the Indianapolis Colts on Monday Night football.

Saints quarterback Drew Brees and Demario Davis lead the pregame huddle before the team prepares to face the Indianapolis COlts on Monday Night Football in the Mercedes-Benz Superdome

New Orleans Saints fans get ready for Monday Night Football in Week 15 against the Indianapolis Colts during our pregame party at Champions Square presented by Ticketmaster.

Follow along with live tweets from the Saints, John DeShazier, Deuce McAllister, Zach Strief, and Caroline Gonzalez throughout the game

Defensive starters Kiko Alonso and Vonn Bell are out

Caroline Gonzalez and John DeShazier preview tonight's match-up vs the Indianapolis Colts on Monday Night Football in the Mercedes-Benz Superdome. Watch on ESPN or listen on WWL 870AM

10 years after Brees brought New Orleans its first Super Bowl victory, he isn't slowing down

Helpful tips and information for New Orleans Week 15 game against Indianapolis

Deeper into the season the games get bigger, the moments are more impactful but the goal remains the same. Watch our hype video to get ready for Monday's game vs. the Colts.

Five Saints players OUT vs. Indianapolis

Get a Week 15 preview from Indianapolis players and coaches

How to watch, listen and live stream New Orleans Saints vs. Indianapolis Colts on December 16, 2019