Buffalo Bills at New Orleans Saints game highlights from Thanksgiving night on Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints center Erik McCoy's postgame interview following the Saints' Thanksgiving night loss to the Buffalo Bills on Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints defensive end Cameron Jordan's postgame interview following the Saints' Thanksgiving night loss to the Buffalo Bills on Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints linebacker Kwon Alexander's postgame interview following the Saints' Thanksgiving night loss to the Buffalo Bills on Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints quarterback Trevor Siemian's postgame interview following the Saints' Thanksgiving night loss to the Buffalo Bills on Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints head coach Sean Payton's postgame interview following the Saints' Thanksgiving night loss to the Buffalo Bills on Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints quarterback Trevor Siemian finds tight end Nick Vannett in the back of the end zone for the touchdown against the Buffalo Bills on Thanksgiving night for Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints quarterback Trevor Siemian stands strong in pocket to deliver 24-yard catch and run to Lil'Jordan Humphrey  against the Buffalo Bills on Thanksgiving night for Thursday Night Football in week 12 of the 2021 NFL season.

Go inside Caesars Superdome for Thursday Night Football as a full capacity crowd give thanks to Drew Brees as he returns the favor on Thanksgiving during halftime of the New Orleans Saints' game vs the Buffalo Bills in week 12 of the 2021 NFL season.

New Orleans Saints linebacker Kwon Alexander intercepts a pass thrown by Buffalo Bills quarterback Josh Allen right before halftime on Thanksgiving night for Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints cornerback Bradley Roby slips around the receiver for the interception off Josh Allen and the Buffalo Bills on Thanksgiving night for Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints linebacker Kaden Elliss goes unblocked to sack Buffalo Bills quarterback Josh Allen on Thanksgiving night for Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints defensive Carl Granderson speeds around the edge and finishes the sack from the ground against Josh Allen and the Buffalo Bills on Thanksgiving night for Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints linebacker Demario Davis gets the Saints hyped up ahead of their game against the Buffalo Bills on Thursday Night Football onn Thanksgiving Night in week 12 of the 2021 NFL season with the Saints Pregame Huddle.

Get hype for the New Orleans Saints' Week 12 Thursday Night Football game against the Buffalo Bills on Thanksgiving day at 7:20 p.m. on NBC.

New Orleans Saints Owner Gayle Benson shares a message to fans ahead of the team's Thanksgiving game against the Buffalo Bills on November 25, 2021.

New Orleans Saints running back Mark Ingram postgame interview following the Saints' loss to the Philadelphia Eagles in week 11 of the 2021 NFL season.

New Orleans Saints safety Marcus Williams postgame interview following the Saints' loss to the Philadelphia Eagles in week 11 of the 2021 NFL season.

New Orleans Saints defensive end Marcus Davenport postgame interview following the Saints' loss to the Philadelphia Eagles in week 11 of the 2021 NFL season.

New Orleans Saints quarterback Trevor Siemian postgame interview following the Saints' loss to the Philadelphia Eagles in week 11 of the 2021 NFL season.

New Orleans Saints head coach Sean Payton postgame interview following the Saints' loss to the Philadelphia Eagles in week 11 of the 2021 NFL season.

Philadelphia Eagles vs New Orleans Saints game highlights from week 11 of the 2021 NFL season.

New Orleans Saints quarterback Trevor Siemian throws the back-shoulder touchdown pass to wide receiver Lil'Jordan Humphrey against the Philadelphia Eagles in week 11 of the 2021 NFL season.

New Orleans Saints quarterback Trevor Siemian runs in the touchdown from 17-yards out against the Philadelphia Eagles in week 11 of the 2021 NFL season.

New Orleans Saints quarterback Trevor Siemian finds wide receiver Marquez Callaway up the middle for the deep touchdown pass against the Philadelphia Eagles in week 11 of the 2021 NFL season.