Saints vs. Cardinals Play-by-Play - Week 1 - Sept. 7, 2025

Check out the 30 best photos of the New Orleans defense in their game against the Arizona Cardinals for Week 1 of the 2025 NFL Season on Sept. 7, 2025 at Caesars Superdome.

Check out the 30 best photos of the New Orleans offense in their game against the Arizona Cardinals for Week 1 of the 2025 NFL Season on Sept. 7, 2025 at Caesars Superdome.

The New Orleans Saints vs. Arizona Cardinals game went down to the wire. Check out a cinematic recap from Week 1 of the 2025 NFL season.

Quotes from Kellen Moore, Justin Reid, Alvin Kamara, Cameron Jordan, and Spencer Rattler

Season-opening win streak snapped in loss to Cardinals

Coach Kellen Moore: 'The story for us and the lesson for us is you can't beat yourself'

Watch full game highlights from the New Orleans Saints vs. Arizona Cardinals game in Week 1 of the 2025 NFL season.

New Orleans Saints tight end Juwan Johnson's postgame interview after the Saints' game vs. the Arizona Cardinals in Week 1 of the 2025 NFL season.

New Orleans Saints center Erik McCoy's postgame interview after the Saints' game vs. the Arizona Cardinals in Week 1 of the 2025 NFL season.

New Orleans Saints cornerback Alontae Taylor's postgame interview after the Saints' game vs. the Arizona Cardinals in Week 1 of the 2025 NFL season.

New Orleans Saints quarterback Spencer Rattler's postgame interview after the Saints' game vs. the Arizona Cardinals in Week 1 of the 2025 NFL season.

New Orleans Saints defensive end Cameron Jordan's postgame interview after the Saints' game vs. the Arizona Cardinals in Week 1 of the 2025 NFL season.

New Orleans Saints running back Alvin Kamara's postgame interview after the Saints' game vs. the Arizona Cardinals in Week 1 of the 2025 NFL season.

New Orleans Saints head coach Kellen Moore's postgame interview after the Saints' game vs. the Arizona Cardinals in Week 1 of the 2025 NFL season.

New Orleans Saints safety Justin Reid's postgame interview after the Saints' game vs. the Arizona Cardinals in Week 1 of the 2025 NFL season.

Saints lose in debut of Coach Kellen Moore as team commits 13 penalties

New Orleans Saints kicker Blake Grupe kicks in the 28-yard field goal vs. the Arizona Cardinals in Week 1 of the 2025 NFL season.

New Orleans Saints defensive back Alontae Taylor rushes untouched to drop Murray for a 15-yard sack in Week 1 of the 2025 NFL season.

New Orleans Saints tight end Juwan Johnson makes a 21-yard gain on a pass from quarterback Spencer Rattler against the Arizona Cardinals in Week 1 of the 2025 NFL season.

Watch highlights of New Orleans Saints defensive tackle Bryan Bresee with the field goal block vs. the Arizona Cardinals in Week 1 of the 2025 NFL.

The Saints Cheer Krewe entertained our fans and Mannie Fresh performed at halftime during the New Orleans Saints game against the Arizona Cardinals in Week 1 of the 2025 NFL season on Sept.7 in the Caesars Superdome.

New Orleans Saints defensive ends Cameron Jordan and Carl Granderson combine to sack Arizona Cardinals quarterback Kyler Murray on third down in Week 1 of the 2025 NFL season.

Check out the game action photos from the New Orleans Saints game against the Arizona Cardinals for Week 1 of the 2025 NFL Season on Sept. 7, 2025 at Caesars Superdome.

Saints will get the ball to start the second half

Watch highlights of New Orleans Saints kicker Blake Grupe knocking through the 36-yard field goal vs. the Arizona Cardinals in Week 1 of the 2025 NFL.