The New Orleans Saints' defense diagnoses and shuts down an end-around attempt by the San Francisco 49ers to the tune of a 4-yard tackle for loss in Week 2 of the 2025 NFL season.

Watch full game highlights from the New Orleans Saints vs. San Francisco 49ers game in Week 2 of the 2025 NFL season.

Watch highlights of New Orleans Saints quarterback Spencer Rattler connecting with wide receiver Devaughn Vele on the 3-yard touchdown pass vs. the San Francisco 49ers in Week 2 of the 2025 NFL.

New Orleans Saints wide receiver Chris Olave leaps to make a 13-yard reception from Spencer Rattler inside the San Francisco 49ers 5-yard line in Week 2 of the 2025 NFL season.

Watch highlights of New Orleans Saints wide reciever Rashid Shaheed pulling in the 3-yard touchdown pass from Spencer Rattler vs. the San Francisco 49ers in Week 2 of the 2025 NFL.

New Orleans Saint quarterback Spencer Rattler uses a juke move to avoid a tackler and pick up first-down yardage on a fourth down vs. the San Francisco 49ers in Week 2 of the 2025 NFL season.

Watch highlights of New Orleans Saints defensive end Chris Rumph II with the strip sack of San Francisco 49ers quarterback Mac Jones recovered by linebacker Demario Davis in Week 2 of the 2025 NFL season.

Watch highlights of New Orleans Saints quarterback Spencer Rattler throwing an 18-yard touchdown pass to tight end Juwan Johnson vs. San Francisco 49ers in Week 2 of the 2025 NFL season.

New Orleans Saints quarterback Spencer Rattler shows off some physicality on a third-down scramble that nets 9 yards vs. the San Francisco 49ers in Week 2 of the 2025 NFL season.

New Orleans Saints tight end Juwan Johnson caps off his first reception of the game with a hurdle to gain first-down yardage vs. the San Francisco 49ers in Week 2 of the 2025 NFL season.

New Orleans Saints quarterback Spencer Rattler connects with wide receiver Brandin Cooks over the middle for a first-down conversion vs. the San Francisco 49ers in Week 2 of the 2025 NFL season.

New Orleans Saints defensive end Carl Granderson is able to stop San Francisco 49ers quarterback Mac Jones from escaping the pocket and drops him for his second sack in Week 2 of the 2025 NFL season.

San Francisco 49ers quarterback Mac Jones attempts to avoid the pass rush of the New Orleans Saints but runs into a sack from defensive end Carl Granderson in Week 2 of the 2025 NFL season.

New Orleans Saints' running back Alvin Kamara puts on a patient running display on his way to a 13-yard gain vs. the San Francisco 49ers in Week 2 of the 2025 NFL season.

Watch highlights of New Orleans Saints wide receiver Rashid Shaheed with the one-handed catch from Spencer Rattler for 39 yards vs. the San Francisco 49ers in Week 2 of the 2025 NFL.

New Orleans Saints linebackers Demario Davis and Pete Werner lead the Saints pregame chant ahead of their game against the San Francisco 49ers in Week 2 of the 2025 NFL season.

New Orleans Saints linebacker Demario Davis leads the Saints Pregame Huddle ahead of their game against the San Francisco 49ers in Week 2 of the 2025 NFL season.

New Orleans Saints head coach Kellen Moore's exclusive interview with team reporter Erin Summers ahead of the Saints' game against the San Francisco 49ers in Week 2 of the 2025 NFL season.

Get HYPE for the New Orleans Saints vs. San Francisco 49ers matchup inside the Caesars Superdome on Sunday, Sept. 14 in Week 2 of the 2025 NFL season!

New Orleans Saints left tackle Kelvin Banks Jr. talks Week 2 with team reporter Erin Summers on What's Brewing presented by Community Coffee.

In honor of Joe Horn's induction into the Louisiana Sports Hall of Fame in 2026, watch highlights of his top career plays with the New Orleans Saints.

The New Orleans Saints vs. Arizona Cardinals game went down to the wire. Check out a cinematic recap from Week 1 of the 2025 NFL season.

Watch full game highlights from the New Orleans Saints vs. Arizona Cardinals game in Week 1 of the 2025 NFL season.

New Orleans Saints tight end Juwan Johnson's postgame interview after the Saints' game vs. the Arizona Cardinals in Week 1 of the 2025 NFL season.

New Orleans Saints center Erik McCoy's postgame interview after the Saints' game vs. the Arizona Cardinals in Week 1 of the 2025 NFL season.