The Saints will open their season at home for the third consecutive season, when they host the Buccaneers (3:25 p.m. CT). It will be the fourth time that the Saints have opened their season against Tampa Bay (2002, 2008 and 2018) and the second time in the past three seasons. New Orleans comes into this contest on a three-game winning streak against Tampa Bay, having swept the Buccaneers last season for the time since 2014.